A Modular Pipeline for Any Project
Kinetic Explorer (KinX) is a fully modular pipeline that can be customized to handle nascent RNA-Seq projects of any scope and size.KinX has been built from the ground up with multithreaded processing and interactive visualizations for rapid results analysis.
KinX Customization
Database Connections
Bring on the "Big Data"
Cloud Infrastructure
Rent as much horsepower as you need
Automated Reporting
Receive updates via SMS text or email
Web Accessibility
View interactive reports over the internet
KinX v1.0 Released
Basic
Web-based and interactive results visualization
Local data storage and compute (up to 2 physical cores on 1 CPU per Basic license)
Two user accounts for data access
Power User (rates apply)
Advanced interactive data visualization and analysis options
Integration of custom data handling rules and kinetic fit equations
Instant-fit: Test and confirm individual kinetic fits
Multiple user accounts as needed
Cloud data storage and multi-node/CPU compute
External and redundant data backup available
Nascent mRNA ProcessingGaribaldi A. et al.
"Isolation of newly transcribed RNA is an invaluable approach that can be used to study the dynamic life of RNA in cellulo. Traditional methods of whole-cell RNA extraction limit subsequent gene expression analyses to the steady-state levels of RNA abundance, which often masks changes in RNA synthesis and processing. This chapter describes a methodology with low cytotoxicity that permits the labeling and isolation of nascent pre-mRNA in cell culture. The resulting isolate is suitable for use in a series of downstream applications aimed at studying changes in RNA synthesis, processing, or stability."